HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromomethylphthalic acid dimethyl ester → (E)-7-[3-(3,4-bis-Hydroxymethylbenzyloxy)phenyl]-3-ethyloct-6-en-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromomethylphthalic acid dimethyl ester | HCID 23255604 | — |
| Reactant | (E)-3-ethyl-7-(3-hydroxyphenyl)oct-6-en-3-ol | HCID 23439826 | — |
| Product | (E)-7-[3-(3,4-bis-Hydroxymethylbenzyloxy)phenyl]-3-ethyloct-6-en-3-ol | HCID 67533486 | 84.3% |
Reaction Steps
In a manner similar to Example 64(d), by reacting 112 mg (0.39 mmol) of (E)-3-ethyl-7-(3-hydroxyphenyl)oct-6-en-3-ol with 145 mg (0.51 mmol) of dimethyl 4-bromomethylphthalate, 131 mg (74%) of expected product are obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689922B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-20ea0a9ee06d4a6bb2c8bb1b96f15a02 |
| Source note | uspto-grants-2004_02 |