HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromomethylphthalic acid dimethyl ester → (Z)-7-[3-(3,4-bis-Hydroxymethylbenzyloxy)phenyl]-3-ethyloct-6-en-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromomethylphthalic acid dimethyl ester | HCID 23255604 | — |
| Reactant | (Z)-3-ethyl-7-(3-hydroxyphenyl)oct-6-en-3-ol | HCID 69685358 | — |
| Product | (Z)-7-[3-(3,4-bis-Hydroxymethylbenzyloxy)phenyl]-3-ethyloct-6-en-3-ol | HCID 11418120 | 92% |
Reaction Steps
In a manner similar to Example 64(d), by reacting 234 mg (0.95 mmol) of (Z)-3-ethyl-7-(3-hydroxyphenyl)oct-6-en-3-ol with 356 mg (1.24 mmol) of dimethyl 4-bromomethylphthalate, .398 mg (92%) of expected product are obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06689922B1 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-edc508c20ac84c23a1feb258494a8fd9 |
| Source note | uspto-grants-2004_02 |