Lithium borohydride → HCID 69685439, compound

HRID 2120483Notes

Reaction equation

[CH2:1]([C:3]([OH:35])([CH2:33][CH3:34])[CH2:4][CH2:5][CH2:6][CH2:7]/[CH:8]=[C:9](\[C:11]1[CH:12]=[C:13]([CH:30]=[CH:31][CH:32]=1)[O:14][CH2:15][C:16]1[CH:17]=[C:18]([C:26](OC)=[O:27])[C:19](=[CH:24][CH:25]=1)[C:20](OC)=[O:21])/[CH3:10])[CH3:2].[BH4-].[Li+]>>[OH:27][CH2:26][C:18]1[CH:17]=[C:16]([CH:25]=[CH:24][C:19]=1[CH2:20][OH:21])[CH2:15][O:14][C:13]1[CH:12]=[C:11](/[C:9](/[CH3:10])=[CH:8]\[CH2:7][CH2:6][CH2:5][CH2:4][C:3]([CH2:1][CH3:2])([OH:35])[CH2:33][CH3:34])[CH:32]=[CH:31][CH:30]=1

Participants

Reactant 2

HCID 4148881Lithium borohydride

HCID 69926302HCID 69926302, compound

Product 1

HCID 69685439HCID 69685439, compound

Procedure

In a manner similar to Example 53(e), by reacting 1.21 g (2.58 mmol) of dimethyl 4-(3-((Z)-7-ethyl-7-hydroxy-1-methylnon-1-enyl)phenoxymethyl]-phthalate (prepared in a manner similar to Example 73(a)) with 170 mg (7.76 mmol) of lithium borohydride, a colourless oil is obtained (m=865 mg; Y=81%).

Workup

customa colourless oil is obtained (m=865 mg; Y=81%)

Sources & evidence

ORD record: ord-9c90bd93cb5a4a528b0bf8ae1c831a10
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06689922B1

Reaction notes

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