Lithium borohydride → HCID 57265283, compound

HRID 2120484Notes

Reaction equation

[OH:1][C:2]([CH3:33])([CH3:32])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH:8]([C:10]1[CH:11]=[C:12]([CH:29]=[CH:30][CH:31]=1)[O:13][CH2:14][C:15]1[CH:16]=[C:17]([C:25](OC)=[O:26])[C:18](=[CH:23][CH:24]=1)[C:19](OC)=[O:20])[CH3:9].[BH4-].[Li+]>>[OH:26][CH2:25][C:17]1[CH:16]=[C:15]([CH:24]=[CH:23][C:18]=1[CH2:19][OH:20])[CH2:14][O:13][C:12]1[CH:11]=[C:10]([CH:8]([CH3:9])[CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][C:2]([CH3:33])([OH:1])[CH3:32])[CH:31]=[CH:30][CH:29]=1

Participants

Reactant 2

HCID 4148881Lithium borohydride

HCID 23439810HCID 23439810, compound

Product 1

HCID 57265283HCID 57265283, compound

Procedure

In a manner similar to Example 53(e), by reacting 97 mg (0.21 mmol) of dimethyl 4-[3-(7-hydroxy-1,7-dimethyloctyl)phenoxymethyl]phthalate (prepared from the previous product in a manner similar to Example 64(d) with 14 mg (0.63 mmol) of lithium borohydride, a colourless oil is obtained (m=83 mg; Y=99%).

Workup

customa colourless oil is obtained (m=83 mg; Y=99%)

Sources & evidence

ORD record: ord-f9ade4febd0f4069be1a6753ad4e935b
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06689922B1

Reaction notes

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