Tetrabutylammonium Fluoride → HCID 86759345, compound

HRID 2120489Notes

Reaction equation

[Si]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:30]=[CH:31][C:32]=1[CH2:33][O:34][Si](C(C)(C)C)(C)C)[O:13][CH2:14][C:15]1[CH:16]=[C:17](/[C:21](/[CH3:29])=[CH:22]/[CH:23]=[CH:24]/[C:25]([CH3:28])([OH:27])[CH3:26])[CH:18]=[CH:19][CH:20]=1)(C(C)(C)C)(C)C.[F-].C([N+](CCCC)(CCCC)CCCC)CCC>>[OH:8][CH2:9][C:10]1[CH:11]=[C:12]([CH:30]=[CH:31][C:32]=1[CH2:33][OH:34])[O:13][CH2:14][C:15]1[CH:16]=[C:17](/[C:21](/[CH3:29])=[CH:22]/[CH:23]=[CH:24]/[C:25]([CH3:26])([OH:27])[CH3:28])[CH:18]=[CH:19][CH:20]=1

Participants

Reactant 2

HCID 2724141Tetrabutylammonium Fluoride

HCID 87950278HCID 87950278, compound

Product 1

HCID 86759345HCID 86759345, compound

Procedure

In a manner similar to Example 57(c), by reacting 120 mg (0.2 mmol) of (3E,5E)-6-{3-[3,4-bis-(tert-butyldimethylsilanyloxymethyl)phenoxymethyl]-phenyl}-2-methylhepta-3,5-dien-2-ol with 0.6 ml of a tetrabutylammonium fluoride solution (1N in THF), a colourless oil is obtained (m=30 mg; Y=41%).

Workup

customa colourless oil is obtained (m=30 mg; Y=41%)

Sources & evidence

ORD record: ord-da13f4132a934106949ef52baec05cbc
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06689922B1

Reaction notes

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