反应详情

In a manner similar to Example 63(c), by reacting 3.9 g (17 mmol) of 3-(5-methoxymethoxy-2-methoxyphenyl)-3-propanone with 8.7 g (34.8 mmol) of ethyl 4-diethylphosphonocrotonate, ethyl 5-(5-methoxymethoxy-2-methoxyphenyl)hepta-2,4-dienoate is obtained which is converted to ethyl 5-(5-hydroxy-2-methoxyphenyl)hepta-2,4-dienoate with concentrated sulphuric acid in ethanol 800 mg (17%).