HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120544Generated: November 1, 2026
Ethanol → sodium 2-(4-(N-salicyloyl)aminophenyl)propionate
https://huagongshe.com/reaction/2120544
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 2-(4-(N-salicyloyl)aminophenyl)propionic acid | HCID 9817303 | — |
| Solvent | Water | HCID 962 | — |
| Product | sodium 2-(4-(N-salicyloyl)aminophenyl)propionate | HCID 23700501 | 92.1% |
Reaction Steps
A solution of 53.05 g (0.186 mol) of 2-(4-(N-salicyloyl)aminophenyl)propionic acid and 300 ml of ethanol was treated with 7.59 g (0.190 mol) of NaOH dissolved in 22 ml of water. The reaction mixture was stirred for 30 min at 25 C and for 30 min at 0° C. The resulting pale yellow solid was isolated by filtration to give 52.61 g of sodium 2-(4-(N-salicyloyl)aminophenyl)propionate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06693073B2 |
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| Source dataset | uspto-grants-2004_02 |
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| ORD ID | ord-b4346d0cbed941d790fee4efbb298836 |
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| Source note | uspto-grants-2004_02 |
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