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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2120546Generated: November 2, 2026

Morpholine → 5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester

https://huagongshe.com/reaction/2120546

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
Reactant5-Chlorocarbonyl-pyridine-2-carboxylic acid methyl esterHCID 15121177—
Product5-(Morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl esterHCID 20622307—

Reaction Steps

In step b, the acid chloride (7) is amidated with morpholine (8) by techniques and procedures well known and appreciated by one of ordinary skill in the art to give the corresponding 5-(morpholine-4-carbonyl)-2-pyridinecarboxylic acid, methyl ester (9).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06693072B2
Source datasetuspto-grants-2004_02
ORD IDord-f44e8e9f9e5e43bf88dc94f8c6462df3
Source noteuspto-grants-2004_02