4-Fluorobenzoyl chloride → 4-Fluoro-N-(5-methoxy-8-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-benzamide

HRID 2120762Notes

Reaction equation

HRID 2120762 reaction equation
[CH3:1][O:2][C:3]1[N:8]2[N:9]=[C:10]([NH2:12])[N:11]=[C:7]2[C:6]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:5][CH:4]=1.[F:19][C:20]1[CH:25]=[CH:24][C:23]([C:26](Cl)=[O:27])=[CH:22][CH:21]=1>>[F:19][C:20]1[CH:25]=[CH:24][C:23]([C:26]([NH:12][C:10]2[N:11]=[C:7]3[C:6]([C:13]4[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=4)=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]3[N:9]=2)=[O:27])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 678794-Fluorobenzoyl chlorideHCID 234358815-Methoxy-8-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl-amine

Product 1

HCID 101092614-Fluoro-N-(5-methoxy-8-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-benzamide

Procedure

According to example 6, the title compound was synthesized from 5-methoxy-8-phenyl-[1,2,4]triazolo[1,5-a]pyridin-2-yl-amine and 4-fluoro-phenyl carboxylic acid chloride.

Sources & evidence

ORD record
ord-1b61d154bfd940d0a5f888347fcec60d
Source dataset
uspto-grants-2004_02
Patent number
US06693116B2

Reaction notes

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