Epibromohydrin → HCID 60111637, compound

HRID 2120890Notes

Reaction equation

[CH2:1]([N:3]([CH2:25][CH3:26])[C:4](=[O:24])[C:5]1[CH:10]=[CH:9][C:8]([C:11]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:12]2[CH2:17][CH2:16][NH:15][CH2:14][CH2:13]2)=[CH:7][CH:6]=1)[CH3:2].[CH2:27]([CH:29]1[O:31][CH2:30]1)Br>>[CH2:25]([N:3]([CH2:1][CH3:2])[C:4](=[O:24])[C:5]1[CH:6]=[CH:7][C:8]([C:11]([C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:12]2[CH2:13][CH2:14][N:15]([CH2:27][CH:29]3[O:31][CH2:30]3)[CH2:16][CH2:17]2)=[CH:9][CH:10]=1)[CH3:26]

Participants

Reactant 2

HCID 18430Epibromohydrin

HCID 9841259ARM390

Product 1

HCID 60111637HCID 60111637, compound

Procedure

Method as described for Example 4, using compound 6 and epibromohydrin (102 mg, 84%):

Sources & evidence

ORD record: ord-1a276a2d4b424f79a109e96183ab077d
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06693117B2

Reaction notes

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