HCID 22975754, compound → HCID 23435720, compound

HRID 2120968Notes

Reaction equation

HRID 2120968 reaction equation
[NH:1]1[CH2:6][CH2:5][CH:4]([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][C:12]3([CH2:19][CH2:18][CH:17]([CH2:20][C:21]([O:23]CC)=[O:22])[CH2:16][CH2:15]3)[CH2:11][CH2:10]2)[CH2:3][CH2:2]1>C(O)C.ClCCl>[NH:1]1[CH2:2][CH2:3][CH:4]([CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][C:12]3([CH2:15][CH2:16][CH:17]([CH2:20][C:21]([OH:23])=[O:22])[CH2:18][CH2:19]3)[CH2:11][CH2:10]2)[CH2:5][CH2:6]1

Participants

4

Reactant 1

HCID 22975754HCID 22975754, compound

Product 1

HCID 23435720HCID 23435720, compound

Reagents, catalysts & solvents 2

HCID 702EthanolCatalystHCID 6344DichloromethaneSolvent

Procedure

0.35 g (1.0 mmol) of the compound from Example 24 were hydrolized in 15 ml ethanol containing 7 drops aqueous sodium hydroxide as described for Example 23. The title acid solidified upon stirring in dichloromethane. It was filtered and dried in vacuo.

Workup

  1. filtrationIt was filtered
  2. customdried in vacuo

Sources & evidence

ORD record
ord-461ce06556844feda0d426f54dae469c
Source dataset
uspto-grants-2004_02
Patent number
US06693109B2

Reaction notes

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