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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 212101Generated: October 25, 2026

Toluene → 5-chloro-1-(2,4-difluorophenyl)-7-ethyl-1H-pyrazolo[4,3-b]pyrazin-6(7H)-one

https://huagongshe.com/reaction/212101

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantPhosphorus oxychlorideHCID 24813—
ReactantDiisopropylethylamineHCID 81531—
ReactantHCID 67197558HCID 67197558—
Product5-chloro-1-(2,4-difluorophenyl)-7-ethyl-1H-pyrazolo[4,3-b]pyrazin-6(7H)-oneHCID 67197346—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-682d866b572c4616af59cdaff435053d
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)