HCID 23436574, compound → 2-(2-Methylphenyl)-4-nitrobenzoic acid

HRID 2121153Notes

Reaction equation

HRID 2121153 reaction equation
C[O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:5]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH3:19].[OH-].[Na+].CO>>[N+:10]([C:7]1[CH:8]=[CH:9][C:4]([C:3]([OH:20])=[O:2])=[C:5]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=2[CH3:19])[CH:6]=1)([O-:12])=[O:11]

Participants

3

Reactant 2

HCID 23436574HCID 23436574, compoundHCID 23721981Sodium hydroxide methanol

Product 1

HCID 234360742-(2-Methylphenyl)-4-nitrobenzoic acid

Procedure

4-Nitro-2-(2-methylphenyl)benzoic acid methyl ester, prepared as in Example 178A, was saponified using aqueous NaOH—CH3OH to give 4-nitro-2-(2-methylphenyl)benzoic acid; HRMS calcd for C14H11NO4 257.0688, obsd 257.0699.

Sources & evidence

ORD record
ord-1392541159ff4065bbdbf17b1891db8a
Source dataset
uspto-grants-2004_02
Patent number
US06693123B2

Reaction notes

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