HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → [4-Azidomethyl-2-phenylbenzoyl]methionine methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | L-Methionine, methyl ester, hydrochloride | HCID 11435579 | — |
| Reactant | 4-Azidomethyl-2-phenylbenzoic acid methyl ester | HCID 54446116 | — |
| Reactant | (4-Amino-2-phenylbenzoyl)methionine methyl ester hydrochloride | HCID 69612387 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [4-Azidomethyl-2-phenylbenzoyl]methionine methyl ester | HCID 20622822 | — |
Reaction Steps
The desired compound was prepared by saponification of the product of Example 332A using sodium hydroxide in refluxing aqueous methanol, followed by coupling of the resulting acid with methionine methyl ester hydrochloride using the procedure of step C in the preparation of compound 8.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06693123B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-0b18c96f3a2040a3b3e3a38bc9362c6d |
| Source note | uspto-grants-2004_02 |