2-(6-Chloro-2-oxo-2,3-dihydrobenzimidazol-1-yl)-3-phenylpropionic acid → 5-chloro-3-[1-oxo-3-phenyl-1-(4-pyridin-4-ylpiperazin-1-yl)propan-2-yl]-1H-benzimidazol-2-one
Reaction equation
[Cl:32][c:33]1[cH:34][cH:35][c:36]2[c:37]([n:38]([CH:42]([C:43](=[O:44])[OH:45])[CH2:46][c:47]3[cH:48][cH:49][cH:50][cH:51][cH:52]3)[c:39](=[O:41])[nH:40]2)[cH:53]1.[O:1]=[C:2]([CH:3]([n:4]1[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]2[nH:11][c:12]1=[O:13])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[N:20]1[CH2:21][CH2:22][N:23]([c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[CH2:24][CH2:25]1>>[N:20]1([C:43]([CH:42]([n:38]2[c:37]3[c:36]([cH:35][cH:34][c:33]([Cl:32])[cH:53]3)[nH:40][c:39]2=[O:41])[CH2:46][c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)=[O:45])[CH2:21][CH2:22][N:23]([c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[CH2:24][CH2:25]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-622d2aa4643b4746a8bd2fa0097e0184
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…