Dichloromethane → (Phenylmethyl) 4-(3-chloro-3-oxopropyl)-1-piperidinecarboxylate

HRID 212140Notes

Reaction equation

HRID 212140 reaction equation
[Cl:26][CH2:27][Cl:28].[S:22]([Cl:23])([Cl:24])=[O:25].[c:1]1([CH2:7][O:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][CH:14]([CH2:17][CH2:18][C:19](=[O:20])[OH:21])[CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([CH2:7][O:8][C:9](=[O:10])[N:11]2[CH2:12][CH2:13][CH:14]([CH2:17][CH2:18][C:19](=[O:21])[Cl:24])[CH2:15][CH2:16]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 24386Thionyl ChlorideHCID 98953153-(1-((Benzyloxy)carbonyl)piperidin-4-yl)propanoic acid

Product 1

HCID 12674069(Phenylmethyl) 4-(3-chloro-3-oxopropyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-9b9c8244c107403bb784df2048033a9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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