Tert-butoxycarbonylalanine → HCID 69735364, compound

HRID 2121512Notes

Reaction equation

[NH2:1][CH:2]1[N:8]=[C:7]([CH:9]([CH3:11])[CH3:10])[C:6]2[CH:12]=[CH:13][CH:14]=[CH:15][C:5]=2[N:4]([CH3:16])[C:3]1=[O:17].C([NH:25][C@H:26]([C:28](O)=[O:29])[CH3:27])(OC(C)(C)C)=O>>[NH2:25][C@H:26]([C:28]([C:2]1([NH2:1])[N:8]=[C:7]([CH:9]([CH3:11])[CH3:10])[C:6]2[CH:12]=[CH:13][CH:14]=[CH:15][C:5]=2[N:4]([CH3:16])[C:3]1=[O:17])=[O:29])[CH3:27]

Participants

Reactant 2

HCID 85082Tert-butoxycarbonylalanine

HCID 10775887HCID 10775887, compound

Product 1

HCID 69735364HCID 69735364, compound

Procedure

Following General Procedure D using 3-amino-2,3-dihydro-5-isopropyl-1-methyl-1H-1,4-benzodiazepin-2-one and N-Boc alanine (Novabiochem), the title compound was prepared as a white solid.

Sources & evidence

ORD record: ord-de8e66fafddf40d5b1fef8709181b766
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06696438B2

Reaction notes

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