Hydrazine → HCID 23433719, compound

HRID 2121621Notes

Reaction equation

HRID 2121621 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:12][CH:11]=[N:10][C:9]=2[C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:4][N:3]=1.[NH2:19][NH2:20]>>[C:13]1([C:9]2[N:10]=[CH:11][O:12][C:8]=2[C:5]2[CH:6]=[CH:7][C:2]([NH:19][NH2:20])=[N:3][CH:4]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

3

Reactant 2

HCID 9321HydrazineHCID 23433750HCID 23433750, compound

Product 1

HCID 23433719HCID 23433719, compound

Conditions

Temperature
70 °C

Procedure

A suspension of 2-Chloro-5-(4-phenyl-oxazol-5-yl)-pyridine (2.55 g, 9.9 mmol) in hydrazine (8 mL) was heated at 70° C. until a solution formed (approximately 20 minutes). The hydrazine product was removed from the heat and concentrated in vacuo affording the above named compound as a dark solid (2.5 g, 100%).

Workup

  1. customformed (approximately 20 minutes)
  2. customThe hydrazine product was removed from the
  3. temperatureheat
  4. concentrationconcentrated in vacuo
  5. customaffording the

Sources & evidence

ORD record
ord-883e5440cc2b493b945a430b6fc610db
Source dataset
uspto-grants-2004_02
Patent number
US06696464B2

Reaction notes

Loading…