2-(2-Chlorophenyl)ethylamine → HCID 23433918, compound

HRID 2121637Notes

Reaction equation

HRID 2121637 reaction equation
I[C:2]1[CH:11]=[C:10]2[C:5]([C:6]([N:13]3[CH2:17][CH2:16][CH2:15][CH2:14]3)=[CH:7][C:8]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1.[Cl:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[CH2:25][CH2:26][NH2:27]>>[Cl:18][C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][C:20]=1[CH2:25][CH2:26][NH:27][C:2]1[CH:11]=[C:10]2[C:5]([C:6]([N:13]3[CH2:17][CH2:16][CH2:15][CH2:14]3)=[CH:7][C:8]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 831172-(2-Chlorophenyl)ethylamineHCID 113366637-Iodo-2-methyl-4-pyrrolidin-1-yl-quinoline

Product 1

HCID 23433918HCID 23433918, compound

Procedure

In analogy to example 1, on reaction of 7-iodo-2-methyl-4-pyrrolidin-1-yl-quinoline with 2-(2-chlorophenyl)-ethylamine there was obtained [2-(2-Chloro-phenyl)-ethyl]-(2-methyl-4-pyrrolidin-1-yl-quinolin-7-yl)-amine as light brown foam. ISP mass spectrum, m/e: 366.2 (M+1 calculated for C22H24ClN3: 366).

Sources & evidence

ORD record
ord-000c3763aa2c4b829354afd7f8f7844d
Source dataset
uspto-grants-2004_02
Patent number
US06696467B2

Reaction notes

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