Acetic Anhydride → HCID 178474260, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of 3-trifluoromethylphenyl-4-amino-2-(5-tetrazolyl)phenyl urea (0.22 g, 0.6 mmol) in 17% aqueous sodium acetate (5 mL), cooled on an ice bath, was added acetic anhydride (1 mL). The reaction was stirred at 0° C. for another hour. The precipitate was filtered off and re-crystallised from 96% ethanol to give 0.12 g of the desired material. M.p. 280-282° C.

Provenance & Evidence