HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2121833Generated: October 27, 2026
Hydrazine hydrate (1:1) → 4-((3-(1,1-Dimethyl-ethyl)phenyl)oxy)-2,5-dimethylaniline
https://huagongshe.com/reaction/2121833
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-Nitro-5-(3-tert-butylphenoxy)-p-xylene | HCID 23434361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | 1-Propanol | HCID 1031 | — |
| Product | 4-((3-(1,1-Dimethyl-ethyl)phenyl)oxy)-2,5-dimethylaniline | HCID 15544590 | — |
Reaction Steps
Hydrazine hydrate (4.3 ml) is added dropwise to a mixture of 1-{[3-(1,1-dimethylethyl)phenyl]oxy}-2,5-dimethyl-4-nitrobenzene (8.65 g) and 5% palladium-on-charcoal (100 mg) in n-propanol (60 ml) heated to 90° C. The reaction mixture is maintained at 90° C. for 2 h and then filtered through Celite. Concentration gives the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06696487B2 |
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| Source dataset | uspto-grants-2004_02 |
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| ORD ID | ord-3f1a4d389994407d964c9b199ed8c624 |
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| Source note | uspto-grants-2004_02 |
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