HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → N'-(2,2-dimethylpropanoyl)-3-methyl-4-nitrobenzhydrazide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Pivaloyl chloride | HCID 62493 | — |
| Reactant | 3-Methyl-4-nitrobenzhydrazide | HCID 3308571 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N'-(2,2-dimethylpropanoyl)-3-methyl-4-nitrobenzhydrazide | HCID 23434365 | — |
Reaction Steps
Water is added to a mixture consisting of 3-methyl-4-nitrobenzhydrazide (3.9 g), triethylamine (3 ml) and 2,2-dimethylpropanoyl chloride (2.6 ml) in dichloromethane (120 ml) stirred for 2 h. After drying, evaporation and trituration of the organic phase in petroleum ether, N′-(2,2-dimethylpropanoyl)-3-methyl-4-nitrobenzhydrazide is obtained in the form of a precipitate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06696487B2 |
| Source dataset | uspto-grants-2004_02 |
| ORD ID | ord-00d7cff5a7d34ef8988a0edf1199532f |
| Source note | uspto-grants-2004_02 |