反应详情

温度

100 °C

A mixture of 2-(1,1-dimethylethyl)-5-(3-methyl-4-nitrophenyl)-1,3,4-oxadiazole (1.6 g), FeCl3.6H2O (5 g) and zinc powder (4 g) in a dimethylformamide/water mixture (1/1, 25 ml) is heated at 100° C. for 30 minutes and then filtered through Celite. After dilution with saturated aqueous sodium carbonate solution, the reaction mixture is extracted with diethyl ether. Drying over magnesium sulphate and evaporation of the organic phase gives the title aniline.

1. filtrationfiltered through Celite
2. extractionAfter dilution with saturated aqueous sodium carbonate solution, the reaction mixture is extracted with diethyl ether
3. dry with materialDrying over magnesium sulphate and evaporation of the organic phase