N-Ethylaniline → Laquinimod

HRID 212188Notes

Reaction equation

HRID 212188 reaction equation
[CH2:1]([CH3:2])[NH:3][c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1.[CH3:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].[Cl:10][c:11]1[c:12]2[c:13]([OH:28])[c:14]([C:23]([O:25][CH2:24][CH3:26])=[O:27])[c:15](=[O:22])[n:16]([CH3:21])[c:17]2[cH:18][cH:19][cH:20]1>>[CH2:1]([CH3:2])[N:3]([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[C:23]([c:14]1[c:13]([OH:28])[c:12]2[c:11]([Cl:10])[cH:20][cH:19][cH:18][c:17]2[n:16]([CH3:21])[c:15]1=[O:22])=[O:25]

Participants

4

Reactant 3

HCID 7670N-EthylanilineHCID 8900HeptaneHCID 54717770Ethyl 5-chloro-4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinoline-3-carboxylate

Product 1

HCID 54677946Laquinimod

Sources & evidence

ORD record
ord-f0558514f58d435387a1ff351fd880b6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

Loading…