Ammonia → HCID 69885696, compound

HRID 2121906Notes

Reaction equation

HRID 2121906 reaction equation
[C:1]([Si:5]([CH3:30])([CH3:29])[O:6][C@H:7]([CH3:28])[CH2:8][N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]3[O:21][CH2:20][C@H:19]([O:22][CH2:23][C:24]([O:26]C)=O)[CH2:18][C:16]3=2)[CH:11]=[N:10]1)([CH3:4])([CH3:3])[CH3:2].[NH3:31]>>[Si:5]([O:6][C@H:7]([CH3:28])[CH2:8][N:9]1[C:17]2[C:12](=[CH:13][CH:14]=[C:15]3[O:21][CH2:20][C@H:19]([O:22][CH2:23][C:24]([NH2:31])=[O:26])[CH2:18][C:16]3=2)[CH:11]=[N:10]1)([C:1]([CH3:2])([CH3:4])[CH3:3])([CH3:29])[CH3:30]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 131724354HCID 131724354, compound

Product 1

HCID 69885696HCID 69885696, compound

Procedure

A solution of the product from Step A (0.49 g, 1.13 mmol) in methanolic ammonia (7 N, 20 mL, 0.14 mol) was stirred for 18 h at room temperature. The reaction mixture was evaporated to a colorless residue (0.44 g, 93%) which was used in the next reaction: LC/MS (+APCI) m/z 420.

Workup

  1. customThe reaction mixture was evaporated to a colorless residue (0.44 g, 93%) which
  2. customwas used in the next reaction

Sources & evidence

ORD record
ord-f42562c76eb34e2784247903b02fe7a4
Source dataset
uspto-grants-2004_02
Patent number
US06696476B2

Reaction notes

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