Fluoride Ion → HCID 69710363, compound

Participants

Reaction Steps

To a mixture of the product from Step C (0.46 g, 1.06 mmol) in THF (50 mL) was added tetrabutylammnium fluoride (1 N in THF, 2.13 mL, 2.13 mmol). The mixture was combined with a saturated aqueous solution of sodium bicarbonate (100 mL) and extracted with ethyl acetate. Chromatography on silica (gradient, 20% to 70% ethyl acetate in hexane) gave an oil (0.39 g): LC/MS (+ESI) m/z 319 (M+H).

Provenance & Evidence