6-Aminoquinoline → HCID 3844778, compound

HRID 2121922Notes

Reaction equation

HRID 2121922 reaction equation
C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:12]([N:14]1[C:18](=[O:19])[C:17](=[C:20]2[N:24]([CH3:25])[C:23]3[CH:26]=[CH:27][CH:28]=[CH:29][C:22]=3[S:21]2)[S:16][CH2+:15]1SC)[CH3:13].[NH2:32][C:33]1[CH:34]=[C:35]2[C:40](=[CH:41][CH:42]=1)[N:39]=[CH:38][CH:37]=[CH:36]2>>[CH2:12]([N:14]1[C:18](=[O:19])[C:17](=[C:20]2[N:24]([CH3:25])[C:23]3[CH:26]=[CH:27][CH:28]=[CH:29][C:22]=3[S:21]2)[S:16][C:15]1=[N:32][C:33]1[CH:34]=[C:35]2[C:40](=[CH:41][CH:42]=1)[N:39]=[CH:38][CH:37]=[CH:36]2)[CH3:13]

Participants

2

Reactant 1

HCID 113736-Aminoquinoline

Product 1

HCID 3844778HCID 3844778, compound

Procedure

The title compound was prepared from 3-ethyl-5-(3-methyl-3H-benzothiazol-2-ylidene)-2-methylthio-4-oxo-2-thiazolium p-toluenesulfonate and 6-aminoquinoline in a manner similar to that described in Example 1. 1H-NMR (CDCl3): δ 8.85 (1H, dd), 8.11 (1H, d), 8.10 (1H, d), 7.51 (1H, dd) 7.46 (1H, dd), 7.40 (1H, d), 7.38 (1H, dd), 7.32 (1H, m), 7.16 (1H, m), 7.01 (1H, d), 4.10 (2H, q), 3.70 (3H, s), 1.41 (3H, t); MS(ESI): 419 (MH+).

Sources & evidence

ORD record
ord-f8615c0163ea4b0d81c74ad91eb4be72
Source dataset
uspto-grants-2004_02
Patent number
US06696473B2

Reaction notes

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