HCID 21937598, compound → HCID 73855025, compound

HRID 2121965Notes

Reaction equation

[CH2:1]([NH:3][C:4]1[CH:16]=[CH:15][C:7]([NH:8][C:9](=[O:14])[C:10]([F:13])([F:12])[F:11])=[CH:6][C:5]=1[N+:17]([O-])=O)[CH3:2].C1(C)C=CC(S([O-])(=O)=O)=CC=1.[CH2:31]([N:38]1[C:42](=[O:43])[C:41](=[C:44]2[N:48]([CH3:49])[C:47]3[CH:50]=[CH:51][CH:52]=[CH:53][C:46]=3[S:45]2)[S:40][CH2+:39]1SC)[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>>[CH2:31]([N:38]1[C:42](=[O:43])[C:41](=[C:44]2[N:48]([CH3:49])[C:47]3[CH:50]=[CH:51][CH:52]=[CH:53][C:46]=3[S:45]2)[S:40][C:39]1=[N:17][C:5]1[CH:6]=[C:7]([NH:8][C:9](=[O:14])[C:10]([F:13])([F:12])[F:11])[CH:15]=[CH:16][C:4]=1[NH:3][CH2:1][CH3:2])[C:32]1[CH:33]=[CH:34][CH:35]=[CH:36][CH:37]=1

Participants

Reactant 1

HCID 21937598HCID 21937598, compound

Product 1

HCID 73855025HCID 73855025, compound

Procedure

In a manner similar to Example 30, intermediate 4′-ethylamino-3′-nitro-2,2,2-trifluoroacetanilide was hydrogenated and then condensed with 3-benzyl-5-(3-methyl-3H-benzothiazol-2-ylidene)-2-methylthio-4-oxo-2-thiazolium p-toluenesulfonate to afford the title compound. MS(ESI): 584 (MH+).

Sources & evidence

ORD record: ord-785f526e89ec4c13b2450ebc334970ce
Source dataset: uspto-grants-2004_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06696473B2

Reaction notes

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