2-Amino-4-(methylthio)butanamide → N-(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)-6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide

HRID 2122475Notes

Reaction equation

HRID 2122475 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:21][CH:22]([C:23](=[O:24])[NH2:25])[CH2:26][CH2:27][S:28][CH3:29]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:21][CH:22]([C:23](=[O:24])[NH2:25])[CH2:26][CH2:27][S:28][CH3:29])[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 5687422-Amino-4-(methylthio)butanamideHCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

Product 1

HCID 71087873N-(1-amino-4-methylsulfanyl-1-oxobutan-2-yl)-6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide

Sources & evidence

ORD record
ord-db8e76cae19b4cb38ed9d389742101f1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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