4-(2,3-Difluoro-phenyl)-1,3-dihydro-indol-2-one → 2-[4-(2,3-Difluoro-phenyl)-2-oxo-1,2-dihydro-indol-3-ylidenemethyl]-5-(2-dimethylamino-ethyl)-3-methyl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one
Reaction equation
[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:17])[c:7]2[c:8]([nH:11][c:12]([CH:15]=[O:16])[c:13]2[CH3:14])[CH2:9][CH2:10]1)[CH3:18].[F:19][c:20]1[c:21](-[c:27]2[c:28]3[c:32]([cH:33][cH:34][cH:35]2)[NH:31][C:30](=[O:36])[CH2:29]3)[cH:22][cH:23][cH:24][c:25]1[F:26]>>[CH3:1][N:2]([CH2:3][CH2:4][N:5]1[C:6](=[O:17])[c:7]2[c:8]([nH:11][c:12]([CH:15]=[C:29]3[c:28]4[c:27](-[c:21]5[c:20]([F:19])[c:25]([F:26])[cH:24][cH:23][cH:22]5)[cH:35][cH:34][cH:33][c:32]4[NH:31][C:30]3=[O:36])[c:13]2[CH3:14])[CH2:9][CH2:10]1)[CH3:18]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-659a6b6815b64b0b8cd9d628bf5bb9cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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