4-(4-Naphthalen-1-yl-piperazin-1-yl)-butan-1-ol → 6-Fluoro-4-methyl-2-[4-(4-naphthalen-1-yl-piperazin-1-yl)-butoxy]-8H-pyrido[2,3-d]pyrimidin-7-one
Reaction equation
[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([S:11]([CH3:12])(=[O:13])=[O:14])[n:8][c:9]2[CH3:10])[nH:15][c:16]1=[O:17].[c:18]1([N:28]2[CH2:29][CH2:30][N:31]([CH2:34][CH2:35][CH2:36][CH2:37][OH:38])[CH2:32][CH2:33]2)[cH:19][cH:20][cH:21][c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]12>>[F:1][c:2]1[cH:3][c:4]2[c:5]([n:6][c:7]([O:38][CH2:37][CH2:36][CH2:35][CH2:34][N:31]3[CH2:30][CH2:29][N:28]([c:18]4[cH:19][cH:20][cH:21][c:22]5[cH:23][cH:24][cH:25][cH:26][c:27]45)[CH2:33][CH2:32]3)[n:8][c:9]2[CH3:10])[nH:15][c:16]1=[O:17]Participants
3
Sources & evidence
- ORD record
- ord-4840179e5e3840539db6e22e11fa543a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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