Zinc → 4-[(4-Bromophenyl)(2,2,6,6-tetramethyltetrahydro-4H-pyran-4-ylidene)methyl]phenol

HRID 212281Notes

Reaction equation

HRID 212281 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)=[C:16]2[CH2:17][CH2:18][O:19][CH2:20][CH2:21]2)[cH:6][cH:7]1.[C:22]1(=[C:23]([c:24]2[cH:25][cH:26][c:27]([OH:28])[cH:29][cH:30]2)[c:31]2[cH:32][cH:33][c:34]([CH:35]=[CH:36][C:37]([NH2:38])=[O:39])[cH:40][cH:41]2)[CH2:42][CH2:43][CH2:44][CH2:45][CH2:46]1.[CH3:47][C:48]1([CH3:57])[O:49][C:50]([CH3:55])([CH3:56])[CH2:51][C:52](=[O:54])[CH2:53]1.[Zn:58]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([C:8]([c:9]2[cH:10][cH:11][c:12]([OH:15])[cH:13][cH:14]2)=[C:52]2[CH2:51][C:50]([CH3:55])([CH3:56])[O:49][C:48]([CH3:47])([CH3:57])[CH2:53]2)[cH:6][cH:7]1

Participants

5

Reactant 4

HCID 23994ZincHCID 118296912,2,6,6-Tetramethyloxan-4-oneHCID 686541974-[(4-Bromophenyl)(tetrahydro-4H-pyran-4-ylidene)methyl]phenolHCID 686545713-[4-[Cyclohexylidene-(4-hydroxyphenyl)methyl]phenyl]prop-2-enamide

Product 1

HCID 686543254-[(4-Bromophenyl)(2,2,6,6-tetramethyltetrahydro-4H-pyran-4-ylidene)methyl]phenol

Sources & evidence

ORD record
ord-78cff92299cd4431ad140149c41ed158
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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