6-(2,4-difluorophenyl)-2-isobutyl-4-methanesulfonyloxym ethyl-2H-pyridazin-3-one → 4-carboxy-2-cinnamyl-6-(4-fluoro-3-methylphenyl)-2H-pyridazin-3-one
Reaction equation
[CH2:26]([CH:27]=[CH:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[n:35]1[n:36][c:37](-[c:46]2[cH:47][c:48]([CH3:53])[c:49]([F:52])[cH:50][cH:51]2)[cH:38][c:39]([C:42](=[O:43])[O:44][CH3:45])[c:40]1=[O:41].[F:1][c:2]1[cH:3][c:4]([F:5])[cH:6][cH:7][c:8]1-[c:9]1[cH:10][c:11]([CH2:12][O:13][S:14]([CH3:15])(=[O:16])=[O:17])[c:18](=[O:19])[n:20]([CH2:21][CH:22]([CH3:23])[CH3:24])[n:25]1>>[CH2:26]([CH:27]=[CH:28][c:29]1[cH:30][cH:31][cH:32][cH:33][cH:34]1)[n:35]1[n:36][c:37](-[c:46]2[cH:47][c:48]([CH3:53])[c:49]([F:52])[cH:50][cH:51]2)[cH:38][c:39]([C:42](=[O:43])[OH:44])[c:40]1=[O:41]Participants
3
Sources & evidence
- ORD record
- ord-ea88fc22a0ea43379aee24719f9e458c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…