7-(benzyloxy)-2,3,4,5-tetrahydro-1H-3-benzazepine → N-Methyl-6-(8-Iodo-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yloxy)-3-pyridinecarboxamide

HRID 212311Notes

Reaction equation

HRID 212311 reaction equation
[CH2:31]([O:32][c:33]1[cH:34][cH:35][c:36]2[c:42]([cH:43]1)[CH2:41][CH2:40][NH:39][CH2:38][CH2:37]2)[c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[I:1][c:2]1[cH:3][c:4]2[c:5]([cH:18][c:19]1[O:20][c:21]1[n:22][cH:23][c:24]([C:27](=[O:28])[NH:29][CH3:30])[cH:25][cH:26]1)[CH2:6][CH2:7][N:8]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH2:9][CH2:10]2>>[I:1][c:2]1[cH:3][c:4]2[c:5]([cH:18][c:19]1[O:20][c:21]1[n:22][cH:23][c:24]([C:27](=[O:28])[NH:29][CH3:30])[cH:25][cH:26]1)[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2

Participants

3

Reactant 2

HCID 574376177-(benzyloxy)-2,3,4,5-tetrahydro-1H-3-benzazepineHCID 574402891,1-Dimethylethyl 7-Iodo-8-({5-[(methylamino)carbonyl]-2-pyridinyl}oxy)-1,2,4,5-tetrahydro-3H-3-benzazepine-3-carboxylate

Product 1

HCID 57440290N-Methyl-6-(8-Iodo-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yloxy)-3-pyridinecarboxamide

Sources & evidence

ORD record
ord-4c3fc71e512441f6875563a7d9291d54
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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