2,6-Dimorpholin-4-ylpyridin-4-amine → N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(2,6-dimorpholinopyridin-4-yl)-N4-methylpyrimidine-2,4-diamine

HRID 212319Notes

Reaction equation

HRID 212319 reaction equation
[Cl:20][c:21]1[n:22][cH:23][cH:24][c:25]([N:27]([CH3:28])[c:29]2[c:30]([Cl:38])[cH:31][cH:32][c:33]3[c:37]2[O:36][CH2:35][O:34]3)[n:26]1.[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][c:9]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[cH:10][c:11]([NH2:13])[cH:12]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][N:4]([c:7]2[n:8][c:9]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[cH:10][c:11]([NH:13][c:21]3[n:22][cH:23][cH:24][c:25]([N:27]([CH3:28])[c:29]4[c:30]([Cl:38])[cH:31][cH:32][c:33]5[c:37]4[O:36][CH2:35][O:34]5)[n:26]3)[cH:12]2)[CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 575713742,6-Dimorpholin-4-ylpyridin-4-amineHCID 581544482-chloro-N-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N-methylpyrimidin-4-amine

Product 1

HCID 42645044N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(2,6-dimorpholinopyridin-4-yl)-N4-methylpyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-2b4586f28aae4fb7a53540e416a630c6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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