2-chloro-N4-(4-chlorophenyl)-5-fluoro-4-pyrimidineamine → (+/-)-N4-(4-chlorophenyl)-N2-(2,3-dihydro-2-methoxycarbonylbenzofuran-5-yl)-5-fluoro-2,4-pyrimidinediamine
Reaction equation
[Cl:15][c:16]1[n:17][cH:18][c:19]([F:30])[c:20]([NH:22][c:23]2[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]2)[n:21]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[CH2:7][CH:8]([C:10](=[O:11])[O:12][CH3:13])[O:9]2>>[NH:1]([c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:14]1)[CH2:7][CH:8]([C:10](=[O:11])[O:12][CH3:13])[O:9]2)[c:16]1[n:17][cH:18][c:19]([F:30])[c:20]([NH:22][c:23]2[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]2)[n:21]1Participants
3
Sources & evidence
- ORD record
- ord-38333fc52a64427f95d5245da1b0be5e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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