Methanol → Ethyl 5-amino-6,7-difluoro-1-(2-fluorocyclopropyl)-8-methyl-4-oxoquinoline-3-carboxylate
Reaction equation
[CH2:29]1[O:30][CH2:31][CH2:32][O:33][CH2:34]1.[CH3:27][OH:28].[F:1][c:2]1[c:3]([N+:24]([O-:25])=[O:26])[c:4]2[c:5](=[O:23])[c:6]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[cH:7][n:8]([CH:14]3[CH:15]([F:17])[CH2:16]3)[c:9]2[c:10]([CH3:13])[c:11]1[F:12]>>[F:1][c:2]1[c:3]([NH2:24])[c:4]2[c:5](=[O:23])[c:6]([C:18](=[O:19])[O:20][CH2:21][CH3:22])[cH:7][n:8]([CH:14]3[CH:15]([F:17])[CH2:16]3)[c:9]2[c:10]([CH3:13])[c:11]1[F:12]Participants
4
Sources & evidence
- ORD record
- ord-8b22ae6dc29b4c2aa81541ebbb873f4d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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