Picolyl chloride → N-[2-[4-[3-methyl-4-(pyridin-2-ylmethoxy)anilino]quinazolin-5-yl]oxypropyl]acetamide
Reaction equation
[Cl:1][CH2:2][c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1.[OH:9][c:10]1[c:11]([CH3:35])[cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][cH:23][cH:24][c:25]([O:27][CH:28]([CH2:29][NH:30][C:31]([CH3:32])=[O:33])[CH3:34])[c:26]23)[cH:14][cH:15]1>>[CH2:2]([c:3]1[n:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([CH3:35])[cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][cH:23][cH:24][c:25]([O:27][CH:28]([CH2:29][NH:30][C:31]([CH3:32])=[O:33])[CH3:34])[c:26]23)[cH:14][cH:15]1Participants
3
Sources & evidence
- ORD record
- ord-5a226ccd1ca744a58166e73bfb9b5ce6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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