Ammonium → 1,1-Dimethylethyl 4-[5-(2-amino-4-pyrimidinyl)-4-(3-{[(2,6-difluorophenyl)sulfonyl]amino}-2-fluorophenyl)-1,3-thiazol-2-yl]-1-piperidinecarboxylate
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:26]3[c:27]([F:44])[c:28]([NH:32][S:33](=[O:34])(=[O:35])[c:36]4[c:37]([F:43])[cH:38][cH:39][cH:40][c:41]4[F:42])[cH:29][cH:30][cH:31]3)[n:10][c:11]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1.[NH4+:45].[OH-:46]>>[c:2]1([NH2:45])[n:3][cH:4][cH:5][c:6](-[c:8]2[c:9](-[c:26]3[c:27]([F:44])[c:28]([NH:32][S:33](=[O:34])(=[O:35])[c:36]4[c:37]([F:43])[cH:38][cH:39][cH:40][c:41]4[F:42])[cH:29][cH:30][cH:31]3)[n:10][c:11]([CH:13]3[CH2:14][CH2:15][N:16]([C:19](=[O:20])[O:21][C:22]([CH3:23])([CH3:24])[CH3:25])[CH2:17][CH2:18]3)[s:12]2)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-9eeef3a7d53c4889a4036fdffc49b2ba
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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