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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 212402Generated: October 26, 2026

Sodium ion → Tert-butyl 3-(3,4-difluorophenyl)-3-hydroxypyrrolidine-1-carboxylate

https://huagongshe.com/reaction/212402

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium ionHCID 923—
ReactantDiethyl EtherHCID 3283—
ReactantCarbonate IonHCID 19660—
Reactant4-Bromo-1,2-difluorobenzeneHCID 67675—
ReactantTert-butyl 3-oxopyrrolidine-1-carboxylateHCID 471360—
ReactantButyllithiumHCID 178418339—
ProductTert-butyl 3-(3,4-difluorophenyl)-3-hydroxypyrrolidine-1-carboxylateHCID 67405004—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-8c35ee650a4445fa9d0ea77f906642d6
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)