3-Chloro-4,7-difluorobenzo[b]thiophene-2-carbonyl chloride → tert-Butyl {4-[(3-chloro-4,7-difluoro-benzo[b]thiophene-2-carbonyl)-(2-ethyl-5-pyridin-4-yl-benzyl)-amino]-cyclohexyl}-methyl-carbamate
Reaction equation
[CH2:1]([CH3:2])[c:3]1[c:4]([CH2:5][NH:6][CH:7]2[CH2:8][CH2:9][CH:10]([N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])[CH2:11][CH2:12]2)[cH:22][c:23](-[c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[cH:24][cH:25]1.[Cl:32][c:33]1[c:34]2[c:35]([s:36][c:37]1[C:38](=[O:39])[Cl:40])[c:41]([F:46])[cH:42][cH:43][c:44]2[F:45]>>[CH2:1]([CH3:2])[c:3]1[c:4]([CH2:5][N:6]([CH:7]2[CH2:8][CH2:9][CH:10]([N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH3:21])[CH2:11][CH2:12]2)[C:38]([c:37]2[c:33]([Cl:32])[c:34]3[c:35]([s:36]2)[c:41]([F:46])[cH:42][cH:43][c:44]3[F:45])=[O:39])[cH:22][c:23](-[c:26]2[cH:27][cH:28][n:29][cH:30][cH:31]2)[cH:24][cH:25]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-abacf61de5ab4397aa648222fde2432a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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