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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2124165Generated: October 26, 2026

N-methyl-2-pyrrolidone → 6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)-8-(3-isoxazolylamino)imidazo[1,2-b]pyridazine-3-carboxamide

https://huagongshe.com/reaction/2124165

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant1,4-DiaminocyclohexaneHCID 18374—
Reactant6-chloro-N-(3-fluoropyridin-4-yl)-8-(isoxazol-3-ylamino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624780—
Product6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)-8-(3-isoxazolylamino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624648—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (4/10)
ORD IDord-78134b23d1654caf884e5b0913b2f62f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (4/10)