(2-Bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanone → [4-Chloro-2-(3-methyl-1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-[4-(3,5-dimethyl-2-pyridinyl)piperazin-1-yl]methanone

HRID 2124534Notes

Reaction equation

HRID 2124534 reaction equation
[Br:1][c:2]1[c:3]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:24])[cH:21][c:22]3[CH3:23])[CH2:15][CH2:16]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[CH3:25][CH:26]1[NH:27][S:28](=[O:31])(=[O:32])[CH2:29][CH2:30]1>>[c:2]1([N:27]2[CH:26]([CH3:25])[CH2:30][CH2:29][S:28]2(=[O:31])=[O:32])[c:3]([C:9](=[O:10])[N:11]2[CH2:12][CH2:13][N:14]([c:17]3[n:18][cH:19][c:20]([CH3:24])[cH:21][c:22]3[CH3:23])[CH2:15][CH2:16]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

3

Reactant 2

HCID 58484730(2-Bromo-4-chlorophenyl)[4-(3,5-dimethylpyridin-2-yl)piperazin-1-yl]methanoneHCID 673808143-Methyl-1,2-thiazolidine 1,1-dioxide

Product 1

HCID 67381259[4-Chloro-2-(3-methyl-1,1-dioxo-1,2-thiazolidin-2-yl)phenyl]-[4-(3,5-dimethyl-2-pyridinyl)piperazin-1-yl]methanone

Sources & evidence

ORD record
ord-cfb8fcb64d2447c499e1afe16dced309
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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