2-(3-Bromo-phenyl)-4-(4-chloro-3-methylphenyl)-6-methyl-pyrimidine → N-tert-Butyl-5-{3-[6-(4-chloro-3-methyl-phenyl)-4-methyl-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

HRID 2125332Notes

Reaction equation

HRID 2125332 reaction equation
[Br:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:22])[cH:11][c:12](-[c:14]3[cH:15][c:16]([CH3:21])[c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1.[C:23]([CH3:24])([CH3:25])([CH3:26])[NH:27][S:28](=[O:29])(=[O:30])[c:31]1[s:32][c:33]([B:36]2[O:37][C:38]([CH3:39])([CH3:40])[C:41]([CH3:42])([CH3:43])[O:44]2)[cH:34][cH:35]1>>[c:2]1(-[c:33]2[s:32][c:31]([S:28]([NH:27][C:23]([CH3:24])([CH3:25])[CH3:26])(=[O:29])=[O:30])[cH:35][cH:34]2)[cH:3][c:4](-[c:8]2[n:9][c:10]([CH3:22])[cH:11][c:12](-[c:14]3[cH:15][c:16]([CH3:21])[c:17]([Cl:20])[cH:18][cH:19]3)[n:13]2)[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 574687912-(3-Bromo-phenyl)-4-(4-chloro-3-methylphenyl)-6-methyl-pyrimidineHCID 57468817N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide

Product 1

HCID 57469056N-tert-Butyl-5-{3-[6-(4-chloro-3-methyl-phenyl)-4-methyl-pyrimidin-2-yl]-phenyl}-thiophene-2-sulfonic acid amide

Sources & evidence

ORD record
ord-fd7368c400044c5a8f18bda118258ca4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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