8-{5-[4-(Trifluoromethyl)phenyl]oxazol-2-ylamino}-3,4-dihydronaphthalen-2(1H)-one → 8-[5-(4-tert-Butylphenyl)oxazol-2-ylamino]-1,2,3,4-tetrahydronaphthalen-2-ol
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][n:13][c:14]([NH:16][c:17]3[cH:18][cH:19][cH:20][c:21]4[c:26]3[CH2:25][C:24](=[O:27])[CH2:23][CH2:22]4)[o:15]2)[cH:9][cH:10]1.[F:28][C:29]([F:30])([F:31])[c:32]1[cH:33][cH:34][c:35](-[c:36]2[o:37][c:38]([NH:39][c:40]3[cH:41][cH:42][cH:43][c:44]4[c:45]3[CH2:46][C:47](=[O:48])[CH2:49][CH2:50]4)[n:51][cH:52]2)[cH:53][cH:54]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[c:5]1[cH:6][cH:7][c:8](-[c:11]2[cH:12][n:13][c:14]([NH:16][c:17]3[cH:18][cH:19][cH:20][c:21]4[c:26]3[CH2:25][CH:24]([OH:27])[CH2:23][CH2:22]4)[o:15]2)[cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-d2908481c73646eeb79e109562c24217
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
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