Glycerol → Ganciclovir Impurity 43

HRID 2125716Notes

Reaction equation

HRID 2125716 reaction equation
[C:26]([CH3:27])(=[O:28])[NH:29][c:30]1[nH:31][c:32](=[O:39])[c:33]2[nH:34][cH:35][n:36][c:37]2[n:38]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH:10]([CH2:11][O:12][CH2:13][c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][O:22][C:23](=[O:24])[CH3:25].[OH:40][CH2:41][CH:42]([CH2:43][OH:44])[OH:45]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][CH2:9][CH:10]([CH2:11][O:12][CH2:13][c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[O:20][CH2:21][n:36]1[cH:35][n:34][c:33]2[c:32](=[O:39])[nH:31][c:30]([NH:29][C:26]([CH3:27])=[O:28])[n:38][c:37]21

Participants

4

Reactant 3

HCID 753GlycerolHCID 11035330Ganciclovir Impurity 42HCID 135432176N-(6,7-dihydro-6-oxo-1H-purin-2-yl)acetamide

Product 1

HCID 135545206Ganciclovir Impurity 43

Sources & evidence

ORD record
ord-0cd70c7d907947b485eff1ba9faac50a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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