(+-)-1-Aminoindan → 4-[(6-Chloropyrimidin-4-yl)amino]-2-(hydroxymethyl)cyclopentan-1-ol

HRID 2125725Notes

Reaction equation

HRID 2125725 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH:11]3[CH:12]([O:13][CH:14]([c:17]4[cH:18][cH:19][c:20]([O:21][CH3:22])[cH:23][cH:24]4)[O:15][CH2:16]3)[CH2:25]2)[n:5][cH:6][n:7]1.[NH2:26][CH:27]1[c:28]2[c:29]([cH:30][cH:31][cH:32][cH:33]2)[CH2:34][CH2:35]1>>[Cl:1][c:2]1[cH:3][c:4]([NH:8][CH:9]2[CH2:10][CH:11]([CH2:16][OH:15])[CH:12]([OH:13])[CH2:25]2)[n:5][cH:6][n:7]1

Participants

3

Reactant 2

HCID 123445(+-)-1-AminoindanHCID 723538876-chloro-N-[2-(4-methoxyphenyl)-4,4a,5,6,7,7a-hexahydrocyclopenta[d][1,3]dioxin-6-yl]pyrimidin-4-amine

Product 1

HCID 723538854-[(6-Chloropyrimidin-4-yl)amino]-2-(hydroxymethyl)cyclopentan-1-ol

Sources & evidence

ORD record
ord-7dcad95bf0414e68a48df9cbb221346f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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