Acetic Acid → 5-Chloro-N-(1,3-dioxo-2-{2-[4-(4-pyridinyl)piperazino]ethyl}-2,3-dihydro-1H-isoindol-4-yl)-2-thiophenecarboxamide

HRID 2125750Notes

Reaction equation

HRID 2125750 reaction equation
[CH3:36][C:37](=[O:38])[OH:39].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][cH:12][cH:13][c:14]3[c:18]2[C:17](=[O:19])[O:16][C:15]3=[O:20])[s:6]1.[n:21]1[cH:22][cH:23][c:24]([N:27]2[CH2:28][CH2:29][N:30]([CH2:33][CH2:34][NH2:35])[CH2:31][CH2:32]2)[cH:25][cH:26]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:7](=[O:8])[NH:9][c:10]2[cH:11][cH:12][cH:13][c:14]3[c:18]2[C:17](=[O:19])[N:35]([CH2:34][CH2:33][N:30]2[CH2:29][CH2:28][N:27]([c:24]4[cH:23][cH:22][n:21][cH:26][cH:25]4)[CH2:32][CH2:31]2)[C:15]3=[O:20])[s:6]1

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 113926535-Chloro-N-(1,3-dioxo-1,3-dihydro-2-benzofuran-4-yl)-2-thiophenecarboxamideHCID 184406752-[4-(4-Pyridinyl)piperazino]ethylamine

Product 1

HCID 103003665-Chloro-N-(1,3-dioxo-2-{2-[4-(4-pyridinyl)piperazino]ethyl}-2,3-dihydro-1H-isoindol-4-yl)-2-thiophenecarboxamide

Sources & evidence

ORD record
ord-8055225de99246d3b53862c1905620b4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

Loading…