5-(2,4-dichlorophenyl)-N-(4-ethoxypyrrolidin-3-yl)-3,6-diethylpyrazin-2-amine → 3,6-diethyl-N-[4-(2-fluoroethoxy)pyrrolidin-3-yl]pyrazin-2-amine

HRID 2125799Notes

Reaction equation

HRID 2125799 reaction equation
[CH2:28]([CH3:29])[c:30]1[c:31]([NH:38][CH:39]2[CH2:40][N:41]([C:48]([O:49][CH2:50][c:51]3[cH:52][cH:53][cH:54][cH:55][cH:56]3)=[O:57])[CH2:42][CH:43]2[O:44][CH2:45][CH2:46][F:47])[n:32][c:33]([CH2:36][CH3:37])[cH:34][n:35]1.[Cl:1][c:2]1[cH:3][c:4]([Cl:5])[cH:6][cH:7][c:8]1-[c:9]1[n:10][c:11]([CH2:12][CH3:13])[c:14]([NH:15][CH:16]2[CH:17]([O:18][CH2:19][CH3:20])[CH2:21][NH:22][CH2:23]2)[n:24][c:25]1[CH2:26][CH3:27]>>[CH2:28]([CH3:29])[c:30]1[c:31]([NH:38][CH:39]2[CH2:40][NH:41][CH2:42][CH:43]2[O:44][CH2:45][CH2:46][F:47])[n:32][c:33]([CH2:36][CH3:37])[cH:34][n:35]1

Participants

3

Reactant 2

HCID 101944255-(2,4-dichlorophenyl)-N-(4-ethoxypyrrolidin-3-yl)-3,6-diethylpyrazin-2-amineHCID 22147388Benzyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

Product 1

HCID 221472343,6-diethyl-N-[4-(2-fluoroethoxy)pyrrolidin-3-yl]pyrazin-2-amine

Sources & evidence

ORD record
ord-5536577ec48444499d3a8ea59131df76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (4/10)

Reaction notes

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