Benzene, 1-(chloromethyl)-2-fluoro- → 4-[(2-Fluorophenyl)methyl]-1-(1-phenylethyl)piperidin-4-ol
Reaction equation
[CH3:10][CH:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH2:20][C:21](=[O:24])[CH2:22][CH2:23]1.[F:1][c:2]1[c:3]([CH2:4][Cl:5])[cH:6][cH:7][cH:8][cH:9]1>>[F:1][c:2]1[c:3]([CH2:4][C:21]2([OH:24])[CH2:20][CH2:19][N:18]([CH:11]([CH3:10])[c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[CH2:23][CH2:22]2)[cH:6][cH:7][cH:8][cH:9]1Participants
3
Sources & evidence
- ORD record
- ord-268f0265514e4a6590ff71dbdf8d8e0f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (4/10)
Reaction notes
Loading…